Cytogenetic anomalies in Multiple Myeloma patients:A single center study.
نویسندگان
چکیده
منابع مشابه
Cytogenetic and molecular aberrations of multiple myeloma patients: a single-center study in Singapore.
BACKGROUND Much is known about the cytogenetic lesions that characterize multiple myeloma (MM) patients from the USA, Europe, and East Asia. However, little has been published about the disease among Southeast Asians. The aim of this study was to determine the chromosomal abnormalities of MM patients in our Singapore population. METHODS Forty-five newly-diagnosed, morphologically confirmed pa...
متن کاملA retrospective analysis of cytogenetic alterations in patients with newly diagnosed multiple myeloma: a single center study in Korea
BACKGROUND The accurate identification of cytogenetic abnormalities in multiple myeloma (MM) has become more important over recent years for the development of new diagnostic and prognostic markers. In this study, we retrospectively analyzed the cytogenetic aberrations in MM cases as an initial assessment in a single institute. METHODS We reviewed the cytogenetic results from 222 patients who...
متن کاملRacial differences in primary cytogenetic abnormalities in multiple myeloma: a multi-center study
We examined four clinically assessed cytogenetic subtypes (t(11;14), t(4;14), monosomy 13/del13q and monosomy 17/del17p in 292 black patients with newly diagnosed multiple myeloma (MM) from four medical centers, who had fluorescent in situ hybridization testing results available in their medical records. We then compared the prevalence of these abnormalities with a previously characterized Mayo...
متن کاملCytogenetic studies in multiple myeloma: a study of fourteen cases.
The bone marrows of fourteen patients with multiple myeloma containing a total of more than twenty scorable metaphase plates in all samples collected were subjected to cytogenetic study. In five of these an abnormal acrocentric marker chromosome with long arms the length of those of the B group was found in a num ber of the hyperdiploid cells. In two additional patients, this same abnormality m...
متن کاملEvaluation of immunomodulatory drugs in multiple myeloma: single center experience.
OBJECTIVE Multiple myeloma (MM) comprises 1% of all cancers and 10% of hematologic malignancies and known as an incurable disease. The introduction of immunomodulatory drugs (IMiDs) has brought a major shift in therapeutic paradigm in the treatment of newly diagnosed and relapsed/refractory MM patients. The aim of this study was to evaluate the relationship between response status and hematolog...
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ژورنال
عنوان ژورنال: Genetics & Applications
سال: 2019
ISSN: 2566-431X,2566-2937
DOI: 10.31383/ga.vol3iss1pp51-56